A single course of antibiotics affects children’s gut microbiota: study


Helsinki: A recent study from the University of Helsinki revealed that the fungal microbiota in the stomachs of children treated with antibiotics is more abundant and diverse than in the control group, even six weeks after the start of antibiotic treatment.

According to the results, antibiotic therapy reduces the amount of gut bacteria, which reduces competition for space and leaves more room for fungi to grow. The research results were published in the Journal of Fungi.

“The results of our study strongly suggest that bacteria in the gut govern and control the fungal microbiome. Fungi, especially Candida, have the ability to multiply when the bacteria are inhibited by antibiotics” Rebecka Ventin-Holmberg, PhD student at the University of Helsinki, accepts.

The major new finding of the study was that changes in the fungal gut microbiota, as well as the bacterial microbiota, may be partly responsible for the long-term negative effects of antibiotics on human health.

Changes in the gut microbiota of infants over time. The most common drugs given to newborns are antibiotics. They alter the intestinal microbiota at its most critical stage of development. Compared to adult alterations, these changes were found to be more durable. “Antibiotics can have negative effects on the bacterial and fungal microbiota, leading for example to antibiotic-associated diarrhoea,” adds Ventin-Holmberg.

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