Staying hydrated while taking spironolactone isn’t always straightforward—too little water can lead to dehydration, while too much can throw off your electrolytes. Learn how to strike the right balance with specific hydration guidelines, practical tips, and a deep dive into what actually happens when you’re on this common medication. This article covers risks, symptoms, and offers actionable steps backed by recent studies. If you take spironolactone for acne, high blood pressure, or hormone-related issues, here’s what you need to know about daily water intake and keeping your body's balance in check.