Ursodeoxycholic Acid (UDCA): What It Is and Why It Matters
Ursodeoxycholic Acid, often called UDCA, is a natural bile acid that doctors use to treat several liver and gallbladder problems. It works by making bile less toxic and helping your liver clear out bad chemicals. If you’ve been told to take UDCA, you’re probably dealing with conditions like primary biliary cholangitis (PBC), certain gallstones, or even some types of liver injury caused by medication.
How UDCA Is Used: Dosage and Typical Regimens
The usual dose for adults is 13‑15 mg per kilogram of body weight per day, split into two doses taken with meals. For a 70‑kg person, that’s roughly 900‑1,050 mg twice a day. Some doctors start you on a lower dose and increase it gradually to avoid stomach upset. If you’re pregnant or nursing, your doctor will weigh the benefits against any potential risks before prescribing.
Common Side Effects and Safety Tips
Most people tolerate UDCA well, but a few may notice mild nausea, diarrhea, or abdominal cramps. These symptoms often fade after a week or two. If you feel severe itching, jaundice, or a rash, call your healthcare provider right away—it could signal an allergic reaction. Always take UDCA with food to reduce stomach irritation, and avoid missing doses because consistency helps keep your liver chemistry stable.
When you pick up your prescription, double‑check the tablet strength and ask the pharmacist any questions about storage—UDCA should stay at room temperature, away from moisture. Some insurance plans cover the medication, but if cost is an issue, ask your doctor about generic versions or patient assistance programs.
Bottom line: UDCA is a handy tool for managing specific liver and gallbladder issues, but like any drug, it works best when you follow dosing instructions, watch for side effects, and keep open communication with your doctor. Got more questions? Your pharmacist or liver specialist can give you the personalized advice you need.
